Itt írjon a(z) lysophosphatidic_acid-ról/ről

Atheroscsclerosis

The effects of lysophosphatidic acid on the vascular system with a in depth look at atherosclerosis. Atherosclerosis is the narrowing of the arteries due to the disposition of plaque. Atherosclerosis is a slowly progressing, multifocal, chronic arterial disease that is characterized by inflammatory and regenerative processes, which lead to matrix remodelling and large lipid deposits. The retention of low-density lipoproteins (LDL) and activation of endothelial cells initiate atherosclerotic lesion formation in the inner layer (intima) of medium and large-sized arteries, such as coronary arteries and cerebral arteries, predominantly at predilection sites, where the laminar blood flow is disturbed (Libby et al., 2011; Weber and Noels, 2011) As cardiac disease is a leading cause of death throughout the Western world, research into this area may prevent the influx in cardiovascular disease in further years to come.